Used in clinical research for immune modulation, particularly in conditions involving excessive interferon-gamma (IFNγ) activity. It has been investigated in autoimmune and inflammatory diseases such as psoriasis and lupus, where blocking IFNγ can reduce disease activity. The antibody helps scientists understand IFNγ pathways and evaluate therapeutic targeting in immune-mediated disorders. It serves as a reference standard in bioassays to measure neutralizing activity and compare efficacy of other anti-IFNγ agents.