Used in immunological research to study cell adhesion and immune cell interactions, particularly in the context of leukocyte migration and activation. Plays a role in investigating inflammatory responses and immune system regulation by targeting ICAM-3 (CD50), a molecule highly expressed on immune cells. This antibody is utilized in assays such as flow cytometry, immunoprecipitation, and functional blocking experiments to modulate immune cell binding and signaling. Due to its specificity, it supports the development of therapeutic strategies for autoimmune diseases, transplant rejection, and cancer immunotherapy. Also serves as a reference tool in the validation of new anti-ICAM-3 antibodies and related biologics.