Used in targeted cancer therapy, particularly for tumors expressing fibronectin, such as melanoma and certain carcinomas. Binds specifically to the extra domain-B of fibronectin, which is present in tumor vasculature but largely absent in healthy tissues, enabling selective delivery of therapeutic agents. Employed as a carrier for radionuclides in radioimmunotherapy, allowing precise irradiation of tumor cells while minimizing damage to surrounding healthy tissue. Also investigated for use in molecular imaging to detect and monitor tumor angiogenesis and metastasis. Its high specificity supports potential applications in diagnostics and image-guided surgery.