Used in the development and validation of assays to measure Factor VIII activity and inhibitor levels in hemophilia A patients. Plays a critical role in quality control during the production of Factor VIII replacement therapies, ensuring product consistency and efficacy. Employed in research settings to study immune responses against Factor VIII, particularly in patients who develop inhibitors, aiding in the design of improved treatment strategies. Supports the standardization of laboratory testing across clinical and pharmaceutical laboratories for accurate diagnosis and monitoring of hemophilia A.