Used in research and therapeutic development targeting tumor progression, inflammation, and viral infections such as coronavirus. Binds to CD147 (also known as EMMPRIN), a protein overexpressed in many cancers and involved in facilitating viral entry into cells. Helps to block interactions that promote tumor cell invasion, metastasis, angiogenesis, and matrix metalloproteinase (MMP) induction. Also explored in autoimmune and inflammatory diseases due to CD147's role in leukocyte migration and activation. Serves as a tool antibody in various laboratory assays, including flow cytometry, immunohistochemistry (IHC), and Western blot, to measure CD147 expression and function in different cancer cell types and other relevant models.