Used in the research and development of diagnostics and therapies for autoimmune diseases, particularly pemphigus vulgaris. Binds specifically to desmoglein 3 (DSG3), a protein involved in cell adhesion in epithelial tissues. This antibody serves as a critical tool for studying disease mechanisms, evaluating drug candidates, and calibrating immunoassays. Enables consistent and reproducible results in assays measuring anti-DSG3 autoantibody levels in patient samples. Also supports the development of targeted biologics by providing a reference for binding affinity and epitope specificity.