Used in research and therapeutic development targeting granulocyte colony-stimulating factor receptor (G-CSFR) signaling pathways. This reference antibody is particularly valuable in studies related to neutrophil regulation, inflammatory diseases, and certain hematological disorders. It serves as a critical tool for validating target engagement, blocking receptor-ligand interactions, and characterizing antibody binding properties in immunoassays. Due to its well-defined specificity and neutralizing activity, it is employed in preclinical development to benchmark biosimilars and novel anti-G-CSFR candidates. Its use extends to in vitro and in vivo models for evaluating immune cell activation and myeloid cell responses.