Used in the treatment of autoimmune and inflammatory conditions involving dysregulated neutrophil production, particularly in patients with chronic neutrophilic leukemia or severe congenital neutropenia. It neutralizes granulocyte colony-stimulating factor (G-CSF), reducing excessive neutrophil activation and associated tissue damage. Investigated in clinical trials for controlling inflammation in diseases such as rheumatoid arthritis and lupus, where G-CSF contributes to disease progression. Also serves as a reference standard in immunoassays and bioassay development for drug monitoring and pharmacokinetic studies.