Used in biomedical research to detect and quantify clathrin heavy chain protein in cells through techniques like Western blotting, immunofluorescence, and immunoprecipitation. Enables study of clathrin-mediated endocytosis, a key cellular process for nutrient uptake, receptor internalization, and synaptic vesicle recycling. Valuable in neuroscience, cancer research, and drug development where endocytic pathways are investigated. Supports high specificity and sensitivity in assays due to its monoclonal nature and validated performance in various experimental models.