Used in targeted cancer therapies, particularly in epithelial-derived tumors where E-cadherin expression is altered. This reference antibody serves as a critical tool in the development of monoclonal antibody-based treatments and diagnostic assays for cancers such as breast, gastric, and ovarian carcinomas. It enables precise detection of E-cadherin on cell surfaces, supporting research in epithelial-mesenchymal transition (EMT), a key process in tumor metastasis. Additionally, it is employed in flow cytometry, immunohistochemistry, and immunoassay standardization within clinical and research laboratories. Its high specificity makes it valuable for stem cell characterization and quality control in regenerative medicine applications.