Used in research and diagnostic applications to detect and quantify CD14 expression on monocytes and macrophages. Helps in studying innate immune responses, particularly in relation to bacterial infections involving lipopolysaccharide (LPS) recognition. Employed in flow cytometry, immunohistochemistry, and ELISA assays to isolate or identify CD14-positive cell populations. Supports development and validation of therapeutic antibodies targeting inflammatory pathways. Also utilized as a reference standard in clinical assays assessing immune activation in conditions like sepsis, autoimmune diseases, and chronic inflammation.