Used in research to detect and study Bcl-2 family proteins, which play key roles in regulating apoptosis (programmed cell death). This antibody helps scientists investigate mechanisms of cell survival and death, particularly in cancer and neurodegenerative diseases. It is commonly applied in techniques like Western blotting, immunohistochemistry, and flow cytometry to monitor protein expression levels and cellular responses to therapeutic agents. Its use supports the development of targeted treatments that modulate apoptotic pathways.