Used in cancer immunotherapy to target CD276 (B7-H3), a protein overexpressed in various tumors such as prostate, breast, lung, and pediatric cancers. It helps the immune system recognize and destroy cancer cells by blocking immune evasion pathways. Investigated in antibody-drug conjugates (ADCs), CAR-T cell therapies, and as a standalone therapeutic or diagnostic agent in tumor imaging. Shows potential for treating solid tumors with limited expression in normal tissues, reducing off-target effects.