H-HomoArg-OH is utilized in peptide synthesis as a building block to create modified peptides with enhanced stability or specific biological activities. It is often incorporated into peptide sequences to study enzyme-substrate interactions, particularly in cases where arginine analogs are required to probe binding sites or modify enzymatic activity. The compound is also used in the development of peptide-based therapeutics, where its structural properties can influence pharmacokinetics and target specificity. Additionally, it finds applications in biochemical research to investigate protein folding and function, as well as in the design of inhibitors for enzymes like proteases. Its unique structure makes it valuable for mimicking natural amino acids in synthetic peptides, enabling the exploration of novel biological pathways and drug candidates.