Di-tert-butyl azodicarboxylate is widely used in organic synthesis as a reagent for the Mitsunobu reaction, which facilitates the conversion of alcohols into esters, ethers, and other derivatives. It is particularly valued for its role in forming carbon-nitrogen and carbon-oxygen bonds under mild conditions. Additionally, it serves as a dehydrogenating agent in the preparation of azo compounds and is employed in the synthesis of pharmaceuticals, agrochemicals, and fine chemicals. Its ability to act as a radical initiator also makes it useful in polymerization processes.