(6-Hydroxyhexyl)triphenylphosphonium bromide
95%
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Used as a mitochondrial-targeting agent in research due to its lipophilic cationic structure. The compound readily crosses cell membranes and accumulates within mitochondria, driven by the organelle's negative membrane potential. Commonly employed in studies involving oxidative stress, mitochondrial dysfunction, and apoptosis. Often conjugated with antioxidants like ubiquinone (e.g., MitoQ analogs) to enhance their delivery to mitochondria. Also utilized in developing probes for mitochondrial imaging and in drug delivery systems aimed at improving therapeutic efficacy in neurodegenerative diseases, cardiovascular conditions, and cancer. Its ability to carry functional groups into mitochondria makes it a valuable tool in biochemical and pharmacological research.
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