(5-(Ethylamino)-5-oxopentyl)triphenylphosphonium bromide
98%
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description Product Description
Used as a mitochondrial-targeting agent in biochemical and pharmacological research. Its primary application lies in delivering bioactive molecules specifically into mitochondria due to the lipophilic cationic nature of the triphenylphosphonium group, which readily crosses lipid membranes and accumulates in the negatively charged mitochondrial matrix. The compound serves as a linker or conjugating agent, especially in the development of mitochondria-targeted antioxidants, drugs, or probes. It enables enhanced cellular uptake and subcellular localization, making it valuable in studies related to oxidative stress, mitochondrial dysfunction, and metabolic diseases. Also employed in the synthesis of novel therapeutic agents where selective mitochondrial delivery improves efficacy and reduces off-target effects.
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