BMS-191095 is primarily investigated for its research applications in the field of cardiology. It is known to act as a selective inhibitor of the mitochondrial ATP-sensitive potassium channel (mitoK_ATP), which is used to study protection of cardiac tissue during ischemic events. By inhibiting these channels, it helps elucidate the role of channel activation in preserving mitochondrial function and reducing cell death, making it a valuable tool for investigating conditions like myocardial infarction. Additionally, its utility is being explored in models of cardiac surgeries involving ischemia-reperfusion or procedures that may compromise heart function. Research continues to explore its mechanisms in preclinical settings.