Mn-TCPP is widely used as a catalyst in oxidation reactions, particularly for the selective oxidation of organic compounds such as alkanes, alkenes, and alcohols. It mimics cytochrome P450 enzymes, making it effective in biomimetic catalysis under mild conditions. The compound is also employed in environmental applications, such as the degradation of organic pollutants in water through activation of oxidants like hydrogen peroxide or peroxymonosulfate. Due to its stability and activity, Mn-TCPP is integrated into sensor systems for detecting reactive oxygen species and in some cases used in photodynamic therapy research for its ability to generate singlet oxygen upon light activation. Additionally, it serves as a building block in porphyrin-based metal-organic frameworks (MOFs) designed for catalytic and sensing applications.