Molybdenum carbide is widely used as a catalyst in industrial chemical processes due to its platinum-like electronic properties. It is particularly effective in hydroprocessing reactions, such as hydrodesulfurization and hydrodenitrogenation, where it helps remove sulfur and nitrogen compounds from crude oil and refined fuels. This contributes to the production of cleaner-burning fuels and reduced environmental pollution.

It also serves as a catalyst in hydrogen evolution reactions, making it valuable in hydrogen production for fuel cells and renewable energy systems. Its high stability under harsh conditions allows for long-term use in high-temperature and corrosive environments.

In addition, molybdenum carbide is used in wear-resistant coatings and cutting tools because of its extreme hardness and thermal stability. It enhances the durability of industrial machinery and extends tool life in metalworking and machining applications. It is also explored in composite materials to improve strength and heat resistance in aerospace and automotive components.