T0901317 is primarily used as a research compound in the study of nuclear receptors, particularly the liver X receptors (LXRs). It acts as a potent synthetic agonist for LXRα and LXRβ, making it a valuable tool for investigating cholesterol metabolism, lipid homeostasis, and inflammatory pathways. Researchers use T0901317 to explore potential therapeutic strategies for atherosclerosis, metabolic disorders, and neurodegenerative diseases due to its ability to modulate genes involved in cholesterol efflux and transport. It has also been employed in studies related to glucose metabolism and insulin sensitivity, showing potential implications in type 2 diabetes research. Additionally, T0901317 has been investigated for its effects on immune responses and its anti-inflammatory properties in cellular and animal models. Due to its broad activity on gene regulation, it serves as a reference compound in drug discovery programs targeting nuclear receptor signaling pathways.