Used as a selective antagonist for the P2Y14 receptor, MS402 is primarily employed in pharmacological research to study purinergic signaling pathways. It helps investigate the role of P2Y14 in immune responses, inflammation, and metabolic disorders. Due to its selectivity, it serves as a valuable tool compound in identifying receptor-specific effects in cellular and animal models, aiding the development of potential therapeutics targeting G-protein-coupled receptors.