Lesinurad sodium is primarily used in the treatment of hyperuricemia associated with gout. It works by inhibiting the URAT1 transporter in the kidneys, which helps to increase the excretion of uric acid. This action reduces the levels of uric acid in the blood, thereby preventing the formation of urate crystals that cause gout symptoms. It is often prescribed in combination with a xanthine oxidase inhibitor, such as allopurinol or febuxostat, to enhance its effectiveness. This combination therapy is particularly beneficial for patients who have not achieved adequate uric acid control with monotherapy. By managing uric acid levels, lesinurad sodium helps to reduce the frequency of gout flares and the progression of gout-related joint damage.