Osteocalcin (1-49) human TFA is widely used in biomedical research to study bone metabolism and its role in regulating energy expenditure and glucose homeostasis. It is employed in experimental models to investigate its influence on osteoblast activity and bone formation. Researchers utilize it to explore its endocrine functions, particularly its effects on insulin secretion and sensitivity. Additionally, it is applied in assays to understand its interaction with other hormones and proteins involved in metabolic processes. This peptide is also used in the development of therapeutic strategies targeting bone-related disorders and metabolic syndromes.