NNGH is widely used in biochemical research, particularly in the study of enzymes and their inhibitors. It is known for its role as a potent inhibitor of matrix metalloproteinases (MMPs), which are enzymes involved in tissue remodeling and degradation. By inhibiting MMPs, NNGH helps researchers investigate the mechanisms of diseases such as cancer, arthritis, and cardiovascular disorders, where MMP activity is often dysregulated. Additionally, NNGH is utilized in drug development to design and test potential therapeutic agents targeting MMP-related pathways. Its application extends to in vitro and in vivo studies, providing valuable insights into enzyme function and the development of targeted treatments.