Ascophyllum Nodosum Extract (Fucoidan Low Molecular Weight 4%, L‑Fucose 1%) is a brown‑seaweed extract rich in fucoidan and free L‑fucose. The low‑molecular‑weight fucoidan fraction supports cosmetic benefits while remaining easy to formulate.
What it does (evidence‑based)
- Soothes visible redness and irritation (anti‑inflammatory pathways)
- Supports the skin barrier and hydration (reduces TEWL)
- Helps defend from UV/photoaging stress (MMP‑1/ROS in models)
- Brightening support via tyrosinase/melanogenesis modulation (LMW fraction)
- Anti‑pollution positioning (fine‑dust oxidative/inflammatory response)
- Microbiome‑friendly: helps reduce adhesion of problem bacteria
- Supports skin recovery (preclinical wound‑repair signals)
- Enzyme inhibition linked to firmness/elasticity (elastase/collagenase)
Note: This ingredient contains fucoidan at 4% and free L‑fucose at 1% within the extract; adjust formula levels to match your claim focus.
Product Description:
Overview
Ascophyllum nodosum extract rich in sulfated polysaccharides contains a low‑molecular‑weight fucoidan fraction (4%) together with free L‑fucose (1%). This composition is designed for soothing, barrier and TEWL support, and urban‑stress/brightening concepts when formulated correctly.
Evidence‑based skin benefits
- Soothing / anti‑inflammatory: Fucoidan modulates NF‑κB/MAPK signaling and lowers NO, TNF‑α and IL‑1β in skin models; topical tests report reduced erythema and better tolerability after UV exposure [1, 2].
- Barrier support & hydration: Fucoidan‑rich treatments decreased transepidermal water loss (TEWL) in clinical settings and supported barrier repair in vivo [3, 4].
- Photoprotection / anti‑photoaging: Inhibits UVB‑induced MMP‑1 in human dermal fibroblasts and reduces ROS, helping preserve dermal matrix [5, 6].
- Brightening: Suppresses tyrosinase/melanogenesis; low‑molecular‑weight (≈5–10 kDa) fractions show the strongest effect [7, 12].
- Anti‑pollution: Low‑MW fucoidan attenuates fine‑dust–induced oxidative/inflammatory cascades in keratinocytes and linked skin cells [8].
- Microbiome‑friendly adhesion control: Inhibits adhesion of S. aureus and C. acnes on reconstructed skin while sparing commensal S. epidermidis [9].
- Skin recovery support: Preclinical data indicate improved wound closure/angiogenesis and faster repair [10].
- Firmness & elasticity mechanisms: Inhibits elastase/collagenase and hyaluronidase in vitro [11].
Technical notes
- Molecular weight & sulfation: Bioactivity depends on MW and degree of sulfation; ≈20% sulfate is commonly associated with strong effects in literature. Low‑MW favors brightening/anti‑pollution, higher MW favors film‑forming/soothing [12].
- Charge/compatibility: Fucoidan is anionic and can interact with cationic polymers/surfactants; verify with a jar test.
L‑Fucose (topical) — complementary role
- Supports visible soothing and comfort (lectin/selectin‑related signaling).
- Helps maintain barrier feel and immediate hydration; pairs well with niacinamide/panthenol/ectoine.
- Acts as a competitive decoy for certain fucose‑binding lectins, reducing pathogen adhesion.
References
- Immunomodulatory and Anti‑Inflammatory Effects of Fucoidan
- Topical Benefits of Two Fucoidan‑Rich Extracts
- Fucoidan‑Rich Polysaccharides: Skin Barrier (TEWL)
- Fucoidan from Undaria pinnatifida — Barrier Repair
- Fucoidan Inhibits UVB‑Induced MMP‑1
- Protective Effects Against UV‑Induced ROS
- Fucoidan and Tyrosinase/Melanogenesis
- Low‑MW Fucoidan and Fine‑Dust Inflammation
- Anti‑Adhesion: S. aureus and C. acnes
- Low‑MW Fucoidan in Wound Healing
- Fucoidan: Elastase/Collagenase/Hyaluronidase
- Size‑Dependent Whitening of Enzyme‑Degraded Fucoidan
- Maritech Fucoidan Portfolio
Usage: Serums, lotions, gels, after‑sun soothing, brightening/anti‑pollution concepts.
Mixing method: Add to the water phase or cool‑down (≤50 °C) and allow full hydration; pH ~4.5–6.5. Fucoidan is anionic and may interact with cationic polymers/surfactants—run a jar test for clarity/viscosity.
Usage rate: 1-10%, recommended 3%
Product characteristics: light colored liquid
Solubility: soluble in water
Storage: Store in the refrigerator. Close the bottle cap tightly. Completely protected from sunlight and heat. The product has a minimum shelf life of 2 years.
INCI Name: : Water, Ascophyllum Nodosum Extract, Phenoxyethanol
Examples of products used Ascophyllum Nodosum Extract
Estee Lauder Re-Nutriv Ultimate Lift Regenerating Youth Eye Creme
LA MER The eye concentrate
Nars Light Reflecting Setting Powder Loose
DR.WU Intensive Hydrating Essence Toner Light
CeraVe Eye Repair Cream
LA MER body lotion
CLINIQUE Redness Solutions Daily Relief Cream With Microbiome Technology
AVEDA tulasāra brightening sleeping eye masque
MiSSHA Premium Cica Aloe Soothing Gel
