AS601245 is primarily used in research settings as a potent and selective inhibitor of JNK (c-Jun N-terminal kinase) signaling pathways. It is widely applied in studies focused on understanding cellular stress responses, apoptosis, and inflammation. Researchers utilize it to investigate its potential therapeutic effects in conditions such as neurodegenerative diseases, ischemia-reperfusion injury, and autoimmune disorders. Additionally, it serves as a valuable tool in preclinical studies to explore its role in modulating oxidative stress and cell survival mechanisms. Its application extends to drug discovery efforts aimed at developing targeted therapies for diseases involving dysregulated JNK activity.