p38 MAPK-IN-2 is primarily utilized in research settings to study the p38 mitogen-activated protein kinase (MAPK) signaling pathway. This pathway plays a critical role in cellular responses to stress, inflammation, and apoptosis. By inhibiting p38 MAPK, this compound helps researchers investigate the mechanisms underlying inflammatory diseases, such as rheumatoid arthritis and chronic obstructive pulmonary disease (COPD). It is also used to explore potential therapeutic strategies for cancer, as p38 MAPK is involved in tumor progression and cell survival. Additionally, p38 MAPK-IN-2 aids in understanding the role of this pathway in neurodegenerative disorders, offering insights into conditions like Alzheimer's disease. Its application extends to drug discovery, where it serves as a tool compound for developing novel inhibitors targeting p38 MAPK-related pathologies.