SKF-86002 dihydrochloride is a potent and selective inhibitor of 5-lipoxygenase (5-LOX), an enzyme critical for the biosynthesis of leukotrienes, which are potent mediators of inflammation and allergic responses. It is primarily used in pharmacological research to investigate inflammatory pathways in diseases such as asthma, arthritis, and rhinitis. By blocking leukotriene production, it aids in understanding the molecular mechanisms of inflammation and evaluating potential anti-inflammatory therapies. The compound also exhibits some inhibitory activity against cyclooxygenase (COX), affecting prostaglandin synthesis. Furthermore, it is employed in studies exploring its impact on cancer cell proliferation, tumor growth, and metastasis, as well as in neuroinflammatory research related to conditions like Alzheimer's disease.