Diethyl 2-[2-fluro-4-biphenyl-4-yl]-2 methylmalonate
97%
Reagent
Code: #50821
Alias
Flurbiprofen Impurity I
CAS Number
42771-81-3
blur_circular Chemical Specifications
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Molecular Information
Weight
344.38 g/mol
Formula
C₂₀H₂₁FO₄
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Storage & Handling
Storage
room temperature
description Product Description
Primarily used as a key intermediate in the synthesis of Valsartan, an angiotensin II receptor blocker (ARB) for treating hypertension, heart failure, and post-myocardial infarction. This chemical facilitates multi-step processes including hydrolysis, decarboxylation, and coupling reactions to form the active pharmaceutical ingredient (API). Its biphenyl and malonate structure enables precise modifications for high efficacy. Additionally, utilized in R&D for developing novel ARB therapeutics with improved cardiovascular profiles. In industrial settings, it optimizes yields and purity in pharmaceutical production.
format_list_bulleted Product Specification
| Test Parameter | Specification |
|---|---|
| Appearance | White to Yellow Crystalline Powder |
| Purity | 96.5-100 |
| NMR | Conforms to Structure |
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