Used primarily as an intermediate in organic synthesis, especially in the production of pharmaceuticals and fine chemicals. Its structure allows for controlled alkylation and functionalization, making it valuable in building complex molecules. Commonly employed in the synthesis of active pharmaceutical ingredients (APIs) where a malonate ester functionality is required for carbon chain extension. Also utilized in fragrance and flavor synthesis due to its ability to form branched esters with desirable olfactory properties. Its steric hindrance from the isobutyl groups influences reaction selectivity, which is advantageous in multi-step syntheses requiring high regio- or stereocontrol.