Widely used in biomedical applications due to their superparamagnetic properties and biocompatibility. Commonly employed in targeted drug delivery, where magnetic guidance allows precise accumulation of therapeutic agents at disease sites, such as tumors. Frequently used in magnetic resonance imaging (MRI) as contrast agents to enhance image clarity and improve diagnosis. Applied in hyperthermia treatment for cancer, where alternating magnetic fields generate localized heat to destroy malignant cells. Also utilized in bioseparation processes, enabling efficient isolation of biomolecules like DNA, proteins, or specific cells using external magnetic fields. The PEG coating enhances stability in physiological environments, reduces immune clearance, and prolongs circulation time in the bloodstream.