1,2,4,5-Tetramethoxybenzene is primarily used in organic synthesis as a building block for more complex molecules. It serves as a precursor in the production of various organic compounds, including pharmaceuticals and agrochemicals. The compound is also utilized in the development of liquid crystals, which are essential components in displays for electronic devices. Additionally, it finds application in the synthesis of dyes and pigments due to its aromatic structure and methoxy groups, which can enhance color properties. In research, it is often employed as a model compound to study reaction mechanisms and chemical behavior in methoxy-substituted aromatic systems.