1-O-hexadecyl-2-acetyl-sn-glycerol (HAG) is primarily used in research and biomedical applications due to its role as a precursor in the synthesis of platelet-activating factor (PAF), a potent lipid mediator involved in various physiological and pathological processes. It is utilized in studies to understand inflammation, immune responses, and cellular signaling pathways. HAG is also employed in the development of pharmacological agents targeting PAF-related disorders, such as allergic reactions, asthma, and cardiovascular diseases. Additionally, it serves as a valuable tool in lipid biochemistry for investigating the structure and function of ether-linked lipids.