NB-598 Maleate is primarily utilized in biochemical research focused on cholesterol biosynthesis. It acts as a potent inhibitor of squalene epoxidase, an enzyme crucial in the cholesterol synthesis pathway. By inhibiting this enzyme, it helps researchers study the effects of reduced cholesterol production in cellular and animal models. This compound is particularly valuable in exploring potential therapeutic strategies for diseases associated with abnormal cholesterol metabolism, such as hypercholesterolemia and certain cardiovascular conditions. Additionally, it aids in understanding the role of cholesterol in various biological processes, including cell membrane integrity and hormone synthesis. Its application extends to pharmacological studies aimed at developing new drugs targeting cholesterol-related disorders.