SB743921 HCl
10mM in DMSO
Reagent
Code: #234046
CAS Number
940929-33-9
blur_circular Chemical Specifications
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Molecular Information
Weight
553.52 g/mol
Formula
C₃₁H₃₃N₂O₃·HCl
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Registry Numbers
MDL Number
MFCD18385010
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Storage & Handling
Storage
-20°C
description Product Description
Used in research as a potent and selective inhibitor of kinesin spindle protein (KSP), making it a candidate for anticancer drug development. It blocks mitotic progression in cancer cells by inhibiting KSP, leading to cell cycle arrest and apoptosis. Studied for its efficacy in tumors resistant to other microtubule-targeting agents, offering potential in treating various solid tumors and hematological malignancies. Its hydrochloride salt form improves solubility and stability for in vitro and in vivo studies.
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