Used in cancer research, particularly as a potent inhibitor of kinesin spindle protein (KSP), which plays a critical role in mitosis. By inhibiting KSP, it blocks the formation of the mitotic spindle, leading to cell cycle arrest and apoptosis in rapidly dividing tumor cells. It has been investigated in preclinical and clinical studies for the treatment of various solid tumors and hematologic malignancies. Its mechanism avoids neurotoxicity commonly seen with microtubule-targeting agents, making it a promising candidate in targeted chemotherapy.