AZ20 is primarily utilized in the field of biomedical research, particularly in the study of cancer. It functions as a potent and selective inhibitor of the ATR kinase, which plays a critical role in the DNA damage response pathway. By inhibiting ATR, AZ20 helps researchers understand the mechanisms of DNA repair and how its disruption can lead to cancer cell death. This makes it a valuable tool in the development of targeted cancer therapies, especially for tumors that are resistant to conventional treatments. Additionally, AZ20 is used in preclinical studies to evaluate its potential as a therapeutic agent in combination with other drugs that induce DNA damage, aiming to enhance the efficacy of cancer treatments.