Aurora kinase inhibitor-2 is primarily utilized in the field of cancer research and therapy. It functions by targeting and inhibiting Aurora kinases, which are enzymes crucial for cell division and proliferation. This inhibition disrupts the mitotic process in cancer cells, leading to their arrest and eventual apoptosis. The compound is particularly significant in studying various cancers, including breast, ovarian, and leukemia, where Aurora kinases are often overexpressed. Additionally, it serves as a valuable tool in preclinical studies to understand the mechanisms of tumor growth and to develop targeted cancer treatments. Its application extends to combination therapies, where it is used alongside other anticancer agents to enhance therapeutic efficacy and overcome drug resistance.