Ki20227 is primarily used in pharmacological research to study the inhibition of the CSF1R enzyme (Colony Stimulating Factor 1 Receptor), which is involved in the growth and function of macrophages and other cells in the immune system. Inhibition of CSF1R can help reduce inflammation and inhibit the growth of certain tumors, particularly in cancers associated with macrophages. Additionally, Ki20227 is used as a tool to investigate the mechanisms of CSF1R function and the development of future anti-cancer drugs.