GW 2580 is primarily utilized in research settings to study its inhibitory effects on colony-stimulating factor 1 receptor (CSF1R). It is a potent and selective inhibitor that helps in understanding the role of CSF1R in various biological processes, particularly in the context of immune system regulation and tumor-associated macrophages. Researchers use GW 2580 to explore its potential in modulating macrophage activity, which is crucial in diseases like cancer, autoimmune disorders, and inflammatory conditions. Its application extends to preclinical studies aimed at developing targeted therapies for conditions where CSF1R signaling plays a significant role.