BIX02189 is primarily used in research settings as a selective inhibitor of MEK5, a kinase involved in the ERK5 signaling pathway. Its application is significant in studying cellular processes such as proliferation, differentiation, and survival, particularly in the context of cancer research. By inhibiting MEK5, BIX02189 helps researchers understand the role of the ERK5 pathway in tumor growth and progression. Additionally, it is utilized in pharmacological studies to explore potential therapeutic strategies targeting this pathway in various diseases, including cardiovascular disorders and inflammation. Its specificity makes it a valuable tool for dissecting the molecular mechanisms underlying these processes.