BIX02188 is primarily used in research settings as a selective inhibitor of MEK5, a kinase involved in the MAPK signaling pathway. Its application is significant in studying cellular processes such as proliferation, differentiation, and apoptosis. Researchers utilize it to explore the role of the MEK5/ERK5 pathway in various diseases, including cancer and cardiovascular conditions. By inhibiting MEK5, it helps in understanding the molecular mechanisms underlying these diseases and aids in the development of targeted therapies. Additionally, BIX02188 is employed in biochemical assays to investigate kinase activity and signaling pathways in vitro. Its specificity makes it a valuable tool for dissecting the functions of MEK5 in cellular and molecular biology studies.