SK1-IN-1 is primarily used in research settings to study the role of sphingosine kinase 1 (SK1) in various biological processes. It is a potent inhibitor of SK1, an enzyme involved in the production of sphingosine-1-phosphate (S1P), a lipid signaling molecule. By inhibiting SK1, this compound helps researchers investigate the enzyme's role in cancer progression, as SK1 is often overexpressed in tumor cells and contributes to cell survival, proliferation, and resistance to chemotherapy. Additionally, SK1-IN-1 is used to explore the involvement of SK1 in inflammatory diseases, as S1P plays a key role in immune cell trafficking and inflammation. Its application extends to studying cardiovascular diseases, where SK1 activity is linked to endothelial dysfunction and atherosclerosis. This compound is a valuable tool for understanding the therapeutic potential of targeting SK1 in various pathological conditions.