([3-(Trifluoromethyl)phenyl]methyl)phosphonic acid
98%
Reagent
Code: #244332
CAS Number
146780-09-8
blur_circular Chemical Specifications
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Molecular Information
Weight
240.12 g/mol
Formula
C₈H₈F₃O₃P
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Storage & Handling
Storage
Room temperature, seal, dry
description Product Description
Used as a key intermediate in the synthesis of pharmaceuticals, particularly in the development of kinase inhibitors and other bioactive molecules. Its phosphonic acid group allows for strong binding to metal ions and enzymes, making it valuable in medicinal chemistry for enhancing metabolic stability and improving target selectivity. Also employed in agrochemical research for designing novel pesticides due to its ability to mimic phosphate esters in biological systems. The trifluoromethylphenyl moiety contributes to increased lipophilicity and electron-withdrawing effects, which can enhance membrane permeability and compound durability in vivo.
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