Tert-Butyl (4-Fluoro-2-Formylphenyl)Carbamate
97%
Reagent
Code: #243852
CAS Number
844891-31-2
blur_circular Chemical Specifications
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Molecular Information
Weight
239.24 g/mol
Formula
C₁₂H₁₄FNO₃
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Storage & Handling
Storage
Room temperature
description Product Description
Used as an intermediate in the synthesis of fluorinated pharmaceutical compounds, particularly in the development of kinase inhibitors and other bioactive molecules. Its aldehyde group allows for further functionalization via reactions such as reductive amination or condensation, enabling the construction of complex heterocyclic structures. The tert-butyl carbamate (Boc) group provides amine protection during peptide or peptidomimetic synthesis, enhancing stability and selectivity in multi-step reactions. Commonly employed in medicinal chemistry for structure-activity relationship (SAR) studies due to the fluorine atom’s influence on metabolic stability, lipophilicity, and binding affinity.
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