TP0463518
10mM in DMSO
Reagent
Code: #239418
CAS Number
1558021-37-6
blur_circular Chemical Specifications
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Molecular Information
Weight
431.83 g/mol
Formula
C₂₀H₁₈ClN₃O₆
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Storage & Handling
Storage
-20°C
description Product Description
Used in research as a potent and selective inhibitor of the enzyme TANK-binding kinase 1 (TBK1), making it a valuable tool compound for studying innate immune signaling pathways, particularly those involving inflammation and antiviral responses. It has also shown potential in oncology research due to TBK1's role in cancer cell survival and proliferation, especially in models of KRAS-driven cancers. Its selectivity allows for targeted modulation of TBK1 without significant off-target effects on related kinases, supporting its use in mechanistic studies and preclinical development.
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