TG-101209
10mM in DMSO
Reagent
Code: #239407
CAS Number
936091-14-4
science Other reagents with same CAS 936091-14-4
blur_circular Chemical Specifications
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Molecular Information
Weight
509.67 g/mol
Formula
C₂₆H₃₅N₇O₂S
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Registry Numbers
MDL Number
MFCD15528085
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Storage & Handling
Storage
-20°C
description Product Description
Used primarily in research settings, this compound functions as a selective inhibitor of Janus kinase 2 (JAK2), making it a valuable tool for studying signaling pathways involved in hematological malignancies. It demonstrates activity against cell lines with JAK2 mutations, particularly those associated with myeloproliferative disorders, allowing scientists to explore targeted therapeutic strategies. Additionally, it has been investigated for its effects on cancer stem cells and its potential to suppress tumor growth in preclinical models. Due to its specificity, it is often employed to dissect JAK-STAT signaling mechanisms in cellular and molecular studies.
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