Trametinib (DMSO solvate)
10mM in DMSO
Reagent
Code: #239294
CAS Number
1187431-43-1
blur_circular Chemical Specifications
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Molecular Information
Weight
693.53 g/mol
Formula
C₂₈H₂₉FIN₅O₅S
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Storage & Handling
Storage
-20°C
description Product Description
Used in cancer treatment, particularly for melanoma with BRAF V600E or V600K mutations. Works as a MEK inhibitor, blocking the activity of the MEK enzyme in the RAS/RAF/MEK/ERK signaling pathway, which controls cell division and survival. By inhibiting this pathway, it helps slow or stop the growth of cancer cells. Often used in combination with BRAF inhibitors like dabrafenib for enhanced efficacy. The DMSO solvate form is typically used in research settings for in vitro studies to maintain stability and solubility.
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