TRi-1 is primarily used as a selective inhibitor in biochemical research, particularly targeting specific kinase enzymes involved in cellular signaling pathways. It has been applied in studies related to inflammation and immune response modulation due to its ability to suppress pro-inflammatory cytokine production. Researchers utilize TRi-1 in cellular assays to investigate pathway mechanisms and validate drug targets, especially in models of autoimmune diseases. Its application extends to cancer research where it helps assess the role of certain kinases in tumor cell proliferation and survival. Due to its cell permeability and stability, TRi-1 is suitable for both in vitro and in vivo experimental models.